Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMO | Q99835 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20108969 | 0.78 | KMT2A (0.53) | HRH4KMT2ASMO | |
| Hydrochloric Acid SCHEMBL21221849 | 0.77 | KMT2A (0.52) | HRH4KMT2ASMO | |
| SCHEMBL20108947 | 0.72 | KMT2A (0.54) | KMT2ASMO | |
| Hydrochloric Acid SCHEMBL21221734 | 0.71 | KMT2A (0.53) | KMT2ASMO | |
| SCHEMBL20108811 | 0.62 | KMT2A (0.41) | KMT2ASMO | |
| SCHEMBL650538 | 0.57 | CHRNB2 (0.74) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL652460 | 0.57 | CHRNB2 (0.74) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL651237 | 0.57 | CHRNB2 (0.74) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL649899 | 0.57 | CHRNB2 (0.72) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL654248 | 0.57 | CHRNB2 (0.72) | CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018080216-A1 | PHENYL PHTHALAZINE DERIVATIVE, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2018-05-03 | — | — | WO | disclosed |