Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 8/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.48 |
| ▸ | SRC | P12931 | 11/20 | 0.41 |
| ▸ | FGR | P09769 | 1/20 | 0.41 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.41 |
| ▸ | TXK | P42681 | 1/20 | 0.41 |
| ▸ | FRK | P42685 | 1/20 | 0.41 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 11/20 | 0.40 |
| ▸ | EGFR | P00533 | 9/20 | 0.40 |
| ▸ | ABL2 | P42684 | 8/20 | 0.40 |
| ▸ | LCK | P06239 | 7/20 | 0.40 |
| ▸ | IGF1R | P08069 | 4/20 | 0.40 |
| ▸ | JAK2 | O60674 | 3/20 | 0.40 |
| ▸ | INSR | P06213 | 3/20 | 0.40 |
| ▸ | RET | P07949 | 3/20 | 0.40 |
| ▸ | KIT | P10721 | 3/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078 | 0.86 | PIK3CD (0.66) | PIK3CDPIK3CGPIK3R1SRCABL1 | |
| SCHEMBL11472 | 0.77 | PIK3CD (0.79) | PIK3CDPIK3CGPIK3R1SRCABL1 | |
| SCHEMBL31655791 | 0.77 | PIK3CD (0.79) | PIK3CDPIK3CGPIK3R1SRCABL1 | |
| SCHEMBL11928103 | 0.73 | PIK3CD (0.61) | PIK3CDPIK3CGPIK3R1SRCABL1 | |
| SCHEMBL10924 | 0.73 | CFTR (0.47) | PIK3R1PIK3CAMAPK14 | |
| SCHEMBL31655806 | 0.72 | PIK3CD (0.69) | PIK3CDPIK3CGPIK3R1SRCABL1 | |
| SCHEMBL11476 | 0.72 | PIK3CD (0.69) | PIK3CDPIK3CGPIK3R1SRCABL1 | |
| SCHEMBL31655803 | 0.71 | PIK3CD (0.69) | PIK3CDPIK3CGPIK3R1SRCABL1 | |
| SCHEMBL11831 | 0.71 | PIK3CD (0.69) | PIK3CDPIK3CGPIK3R1SRCABL1 | |
| SCHEMBL8581 | 0.69 | PIK3CD (0.83) | PIK3CDPIK3CGPIK3R1SRCABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118754-A1 | COMPOUNDS | RESPIVERT LTD. (GB) | 2018-05-03 | — | — | US | disclosed |
| US-20180118754-A1 | COMPOUNDS | RESPIVERT LTD. (GB) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118754-A1 | COMPOUNDS | LTC4S, CYP11B2, LTB4R2 | PIK3CD 4224/4885PIK3CG 3708/4885PIK3R1 4842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.