SCHEMBL20108858

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20108853	0.89	TOP1 (0.38)	TOP1CYP2C9TP53HIF1A
	SCHEMBL20108882	0.89	PARP1 (0.40)	TOP1PARP1CYP1A1CYP1B1NQO2
	SCHEMBL20108900	0.88	CYP2C9 (0.39)	TOP1DHODHCYP2C9TP53HSD17B10
	SCHEMBL20108860	0.86	TOP1 (0.38)	TOP1PARP1DHODHCYP1A1CYP1B1
	SCHEMBL15479318	0.85	ESR1 (0.39)	TOP1CYP2C9CYP1A2CYP2C19ESR1
	SCHEMBL20250370	0.83	CYP1A1 (0.46)	PARP1CYP1A1CYP1B1CYP2C9TP53
	SCHEMBL17403775	0.83	PARP1 (0.46)	TOP1PARP1PIM1PIM2
	SCHEMBL20108903	0.83	CYP1A1 (0.37)	TOP1PARP1DHODHCYP1A1CYP1B1
	SCHEMBL20108862	0.83	TOP1 (0.39)	TOP1PARP1DHODHCYP1A1CYP1B1
	SCHEMBL17451937	0.83	TOP1 (0.38)	TOP1PARP1DHODHCYP1A1CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.