SCHEMBL20108882

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17403775	0.91	PARP1 (0.46)	PARP1TOP1MEN1RAB9AKMT2A
	SCHEMBL20108903	0.91	CYP1A1 (0.37)	PARP1CYP1A1CYP1B1CYP11B1CYP11B2
	SCHEMBL20108846	0.90	CYP1A1 (0.45)	PARP1ESR1ESR2CYP1A1CYP1B1
	SCHEMBL20108852	0.90	TOP1 (0.41)	PARP1CYP11B1CYP11B2CYP17A1CYP19A1
	SCHEMBL20108858	0.89	TOP1 (0.38)	PARP1ESR1ESR2CYP1A1CYP1B1
	SCHEMBL20108860	0.89	TOP1 (0.38)	PARP1CYP1A1CYP1B1TOP1NQO2
	SCHEMBL17174105	0.88	PARP1 (0.46)	PARP1CYP1A1CYP1B1CYP19A1TOP1
	SCHEMBL17174127	0.88	PARP1 (0.46)	PARP1CYP1A1CYP1B1CYP19A1TOP1
	SCHEMBL17174111	0.87	PARP1 (0.41)	PARP1CYP11B1CYP11B2CYP19A1TOP1
	SCHEMBL14020765	0.87	PARP1 (0.47)	PARP1CYP1A1CYP1B1CYP19A1TOP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.