Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20109340 | 0.95 | MMP8 (0.39) | MMP8ALDH1A1TP53TACR1L3MBTL1 | |
| SCHEMBL20109220 | 0.90 | MMP8 (0.36) | MMP8ALDH1A1TP53TACR1L3MBTL1 | |
| SCHEMBL20109245 | 0.90 | MMP8 (0.36) | MMP8ALDH1A1TP53TACR1L3MBTL1 | |
| SCHEMBL17596815 | 0.86 | MMP8 (0.50) | MMP8ALDH1A1TP53L3MBTL1TDP1 | |
| SCHEMBL21866401 | 0.85 | MMP8 (0.39) | MMP8ALDH1A1TP53TACR1L3MBTL1 | |
| SCHEMBL20109149 | 0.85 | MMP8 (0.44) | MMP8ALDH1A1TP53L3MBTL1TDP1 | |
| SCHEMBL20113634 | 0.85 | MMP8 (0.38) | MMP8ALDH1A1TP53TACR1L3MBTL1 | |
| SCHEMBL20113430 | 0.85 | MMP8 (0.38) | MMP8ALDH1A1TP53TACR1L3MBTL1 | |
| SCHEMBL20109357 | 0.81 | MMP8 (0.43) | MMP8ALDH1A1TP53L3MBTL1KDM4E | |
| SCHEMBL17595866 | 0.81 | MMP8 (0.46) | MMP8ALDH1A1TP53L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | NANP, PPIP5K2, PHPT1 | MMP8 4444/4885ALDH1A1 4621/4885TP53 1611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.