Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20109164 | 0.78 | ZDHHC7 (0.35) | ZDHHC7GPR84L3MBTL1TDP1MEN1 | |
| SCHEMBL6828633 | 0.75 | TDP1 (0.50) | ZDHHC7GPR84L3MBTL1TDP1MEN1 | |
| SCHEMBL7508355 | 0.75 | TDP1 (0.50) | ZDHHC7GPR84L3MBTL1TDP1MEN1 | |
| SCHEMBL5849644 | 0.75 | TDP1 (0.50) | ZDHHC7GPR84L3MBTL1TDP1MEN1 | |
| SCHEMBL182928 | 0.75 | TDP1 (0.50) | ZDHHC7GPR84L3MBTL1TDP1MEN1 | |
| SCHEMBL10017368 | 0.75 | TDP1 (0.50) | ZDHHC7GPR84L3MBTL1TDP1MEN1 | |
| SCHEMBL4416096 | 0.75 | TDP1 (0.50) | ZDHHC7GPR84L3MBTL1TDP1MEN1 | |
| SCHEMBL9116048 | 0.75 | TDP1 (0.50) | ZDHHC7GPR84L3MBTL1TDP1MEN1 | |
| SCHEMBL2948251 | 0.75 | TDP1 (0.50) | ZDHHC7GPR84L3MBTL1TDP1MEN1 | |
| SCHEMBL5860379 | 0.75 | TDP1 (0.50) | ZDHHC7GPR84L3MBTL1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10633403-B2 | N-heterocyclic phosphines | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA (US) | 2020-04-28 | — | — | US | disclosed |
| US-20180118770-A1 | N-Heterocyclic Phosphines | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2018-05-03 | — | — | US | disclosed |
| US-20180118770-A1 | N-Heterocyclic Phosphines | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | NANP, PPIP5K2, PHPT1 | ZDHHC7 2691/4885GPR84 4554/4885L3MBTL1 3799/4885 |
| US-10633403-B2 | N-heterocyclic phosphines | NANP, PPIP5K2, PHPT1 | ZDHHC7 2691/4885GPR84 4554/4885L3MBTL1 3799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.