Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 6/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20113633 | 0.87 | TDP1 (0.39) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL20109144 | 0.86 | NPSR1 (0.32) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL20109230 | 0.85 | GAA (0.34) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL20113532 | 0.81 | MAPT (0.40) | NPSR1ALDH1A1LMNAKMT2AGAA | |
| SCHEMBL20109257 | 0.75 | ALDH1A1 (0.33) | ALDH1A1LMNATSHRKMT2AGAA | |
| SCHEMBL20113543 | 0.74 | ALDH1A1 (0.44) | NPSR1ALDH1A1LMNAKMT2ANPC1 | |
| SCHEMBL20109345 | 0.74 | TDP1 (0.39) | ALDH1A1LMNATSHRKMT2AMAPT | |
| SCHEMBL20113433 | 0.73 | TDP1 (0.38) | ALDH1A1LMNAKMT2AMAPTKDM4E | |
| SCHEMBL17596727 | 0.70 | MAPT (0.40) | ALDH1A1KMT2AGAAMAPT | |
| SCHEMBL20109255 | 0.70 | HTT (0.33) | ALDH1A1TSHRKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | NANP, PPIP5K2, PHPT1 | HDAC3 1176/4885HDAC4 1531/4885HDAC1 1748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.