SCHEMBL20110397

SCHEMBL20110397

CC(=O)Oc1ccc(C(=O)Oc2ccc(OC(=O)c3ccc(C)cc3)cc2C(C)=O)cc1

nearest known ligand 0.65

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.65
KDM4E B2RXH2 1/20 0.65
POLB P06746 1/20 0.65
MAPK1 P28482 1/20 0.65
KMT2A Q03164 8/20 0.59
LMNA P02545 2/20 0.54
PRSS1 P07477 1/20 0.47
ACR P10323 1/20 0.47
GBA1 P04062 1/20 0.46
MEN1 O00255 1/20 0.45
GAA P10253 1/20 0.44
HPGD P15428 1/20 0.44
TP53 P04637 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17301247 0.94 MAPT (0.72) MAPTKDM4EPOLBMAPK1KMT2A
SCHEMBL20110390 0.90 MAPT (0.52) MAPTKDM4EPOLBMAPK1KMT2A
SCHEMBL17301248 0.89 KMT2A (0.70) MAPTKDM4EPOLBMAPK1KMT2A
SCHEMBL14370325 0.86 LMNA (0.57) MAPTKDM4EPOLBMAPK1KMT2A
SCHEMBL14484181 0.86 LMNA (0.57) MAPTKDM4EPOLBMAPK1KMT2A
SCHEMBL14370321 0.86 LMNA (0.57) MAPTKDM4EPOLBMAPK1KMT2A
SCHEMBL17301250 0.86 MAPT (0.61) MAPTKDM4EPOLBMAPK1KMT2A
SCHEMBL19054604 0.84 LMNA (0.62) MAPTKDM4EPOLBMAPK1KMT2A
SCHEMBL14370322 0.84 LMNA (0.77) MAPTKMT2ALMNAPRSS1ACR
SCHEMBL14484261 0.84 LMNA (0.77) MAPTKMT2ALMNAPRSS1ACR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180119014-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL POLYMERIZED FILMS JNC CORPORATION (JP) 2018-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180119014-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL POLYMERIZED FILMS NAP1L1, CCNA1, NAP1L4 MAPT 371/4885KDM4E 2829/4885POLB 1874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.