SCHEMBL20110427

SCHEMBL20110427

c1cc(-c2ccc(-c3cccc(-n4c5ccccc5c5ccccc54)c3)s2)cc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.52
▸ KDM4E B2RXH2 1/20 0.52
▸ ATM Q13315 1/20 0.52
▸ HSD17B1 P14061 10/20 0.44
▸ HSD17B2 P37059 10/20 0.44
▸ KMT2A Q03164 2/20 0.36
▸ NQO2 P16083 2/20 0.36
▸ IL1R1 P14778 1/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ PRF1 P14222 4/20 0.35
▸ CYP3A4 P08684 2/20 0.34
▸ CYP2D6 P10635 2/20 0.34
▸ CYP2C19 P33261 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12546443 0.98 L3MBTL1 (0.55) L3MBTL1KDM4EATMHSD17B1HSD17B2
SCHEMBL31357350 0.90 L3MBTL1 (0.42) L3MBTL1KDM4EATMHSD17B1HSD17B2
SCHEMBL23044992 0.89 L3MBTL1 (0.67) L3MBTL1KDM4EATMHSD17B1HSD17B2
SCHEMBL14208768 0.89 L3MBTL1 (0.44) L3MBTL1KDM4EATMHSD17B1HSD17B2
SCHEMBL12546406 0.87 L3MBTL1 (0.44) L3MBTL1KDM4EATMHSD17B1HSD17B2
SCHEMBL12288637 0.87 KDM4E (0.50) L3MBTL1KDM4EATMALDH1A1MAPT
SCHEMBL12362792 0.87 L3MBTL1 (0.55) L3MBTL1KDM4EATMHSD17B1HSD17B2
SCHEMBL20110428 0.87 KDM4E (0.48) L3MBTL1KDM4EATMHSD17B1HSD17B2
SCHEMBL29384509 0.85 ATM (0.64) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL29432855 0.85 ATM (0.64) L3MBTL1KDM4EATMKMT2AIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210005827-A1 N AND P ACTIVE MATERIALS FOR ORGANIC PHOTOELECTRIC CONVERSION LAYERS IN ORGANIC PHOTODIODES SONY CORPORATION (JP) 2021-01-07 — — US disclosed
US-10790454-B2 N and P active materials for organic photoelectric conversion layers in organic photodiodes SONY CORPORATION (JP) 2020-09-29 — — US disclosed
US-20180123050-A1 N AND P ACTIVE MATERIALS FOR ORGANIC PHOTOELECTRIC CONVERSION LAYERS IN ORGANIC PHOTODIODES SONY CORPORATION (JP) 2018-05-03 — — US disclosed
US-20180123050-A1 N AND P ACTIVE MATERIALS FOR ORGANIC PHOTOELECTRIC CONVERSION LAYERS IN ORGANIC PHOTODIODES SONY CORPORATION (JP) 2018-05-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10790454-B2 N and P active materials for organic photoelectric conversion layers in organic photodiodes L1CAM, PNN, JUP L3MBTL1 2719/4885KDM4E 1801/4885ATM 847/4885
US-20180123050-A1 N AND P ACTIVE MATERIALS FOR ORGANIC PHOTOELECTRIC CONVERSION LAYERS IN ORGANIC PHOTODIODES L1CAM, PNN, JUP L3MBTL1 2719/4885KDM4E 1801/4885ATM 847/4885
US-20210005827-A1 N AND P ACTIVE MATERIALS FOR ORGANIC PHOTOELECTRIC CONVERSION LAYERS IN ORGANIC PHOTODIODES L1CAM, PNN, JUP L3MBTL1 2719/4885KDM4E 1801/4885ATM 847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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