SCHEMBL20111235

SCHEMBL20111235

CCCCc1cc2c(c(F)c1F)-c1c-2ccc(C)c1F

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.37
SKP2 Q13309 1/20 0.33
MEN1 O00255 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
ALOX5 P09917 1/20 0.32
MAPT P10636 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
GCGR P47871 1/20 0.31
ELANE P08246 1/20 0.31
CTSG P08311 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20102401 0.84 TYR (0.41) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL20111585 0.83 CTSL (0.36)
SCHEMBL20102402 0.81 TYR (0.40) TYRSKP2MEN1TP53CYP3A4
SCHEMBL20102398 0.80 TYR (0.41) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL20102399 0.80 TYR (0.41) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL20111206 0.79
SCHEMBL20102400 0.79 TYR (0.43) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL20102500 0.78 CTSL (0.40) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL21919583 0.77 TYR (0.41) TYRSKP2MEN1TP53CYP3A4
SCHEMBL12238347 0.76 TYR (0.46) TYRSKP2MEN1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10323187-B2 Liquid crystal compound having biphenylene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2019-06-18 US disclosed
US-20180119009-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180119009-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE YBX1, PIEZO1, C1S TYR 714/4885SKP2 893/4885MEN1 2571/4885
US-10323187-B2 Liquid crystal compound having biphenylene, liquid crystal composition and liquid crystal display device YBX1, PIEZO1, C1S TYR 714/4885SKP2 893/4885MEN1 2571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.