SCHEMBL20111292

SCHEMBL20111292

CCCc1cc2c(c(F)c1F)-c1c-2ccc(-c2ccc(C3CCC(C)CC3)cc2)c1F

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.35
FASN P49327 1/20 0.35
FFAR4 Q5NUL3 1/20 0.32
CYP3A4 P08684 2/20 0.31
CYP2C9 P11712 2/20 0.31
APP P05067 2/20 0.31
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20111244 0.86 CYP3A4 (0.37) ESR2FASNFFAR4CYP3A4CYP2C9
SCHEMBL20102577 0.86 MEN1 (0.34) ESR2FFAR4CYP3A4CYP2C9
SCHEMBL18511927 0.85 ESR2 (0.41) ESR2FASNFFAR4CYP3A4CYP2C9
SCHEMBL20102579 0.83 MEN1 (0.33) ESR2CYP2C9
SCHEMBL20111485 0.83
SCHEMBL20102612 0.81 SPHK1 (0.36) CYP2C9
SCHEMBL20111497 0.81 ESR2 (0.45) ESR2FASNFFAR4CYP3A4CYP2C9
SCHEMBL20111366 0.80
SCHEMBL20111534 0.80 SPHK1 (0.37) FASNFFAR4
SCHEMBL20111722 0.79 CTSL (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10323187-B2 Liquid crystal compound having biphenylene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2019-06-18 US disclosed
US-20180119009-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180119009-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE YBX1, PIEZO1, C1S ESR2 1639/4885FASN 2680/4885FFAR4 309/4885
US-10323187-B2 Liquid crystal compound having biphenylene, liquid crystal composition and liquid crystal display device YBX1, PIEZO1, C1S ESR2 1639/4885FASN 2680/4885FFAR4 309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.