SCHEMBL20111360

SCHEMBL20111360

Fc1ccc2c(c1F)-c1c-2ccc(OCC2CCCC2)c1F

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.40
SLC6A4 P31645 1/20 0.40
HTR6 P50406 1/20 0.40
PARP10 Q53GL7 3/20 0.38
ALOX5AP P20292 2/20 0.38
FEN1 P39748 2/20 0.38
MCHR1 Q99705 2/20 0.37
PARP15 Q460N3 2/20 0.36
FABP4 P15090 1/20 0.36
FABP5 Q01469 1/20 0.36
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20117898 0.81 HPGD (0.39) FFAR1SLC6A4HTR6
SCHEMBL26770383 0.81 HTR2A (0.44) FFAR1SLC6A4HTR6PARP10MCHR1
SCHEMBL16501544 0.81 SLC6A4 (0.47) SLC6A4HTR6PARP10MCHR1PARP15
SCHEMBL20102467 0.80 PTGDR2 (0.37) FFAR1SLC6A4HTR6
SCHEMBL26770373 0.78 HTR2C (0.44) FFAR1SLC6A4HTR6PARP10ALOX5AP
SCHEMBL18466652 0.78 MCHR1 (0.50) SLC6A4PARP10MCHR1
SCHEMBL26505542 0.76 SLC6A4 (0.39) FFAR1SLC6A4HTR6PARP10MCHR1
SCHEMBL1500529 0.76 SLC6A4 (0.43) FFAR1SLC6A4HTR6PARP10MCHR1
SCHEMBL20111289 0.76 SLC6A4 (0.35) SLC6A4HTR6PARP10ALOX5APFEN1
SCHEMBL26770363 0.75 HTR2C (0.47) PARP10PARP15HTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10323187-B2 Liquid crystal compound having biphenylene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2019-06-18 US disclosed
US-20180119009-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180119009-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE YBX1, PIEZO1, C1S FFAR1 536/4885SLC6A4 2219/4885HTR6 2692/4885
US-10323187-B2 Liquid crystal compound having biphenylene, liquid crystal composition and liquid crystal display device YBX1, PIEZO1, C1S FFAR1 536/4885SLC6A4 2219/4885HTR6 2692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.