Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20111628 | 0.89 | MCOLN3 (0.40) | MCOLN3MEN1KMT2ATDP1LMNA | |
| SCHEMBL21732885 | 0.81 | CYP2D6 (0.47) | — | |
| SCHEMBL20111913 | 0.79 | POLB (0.34) | MEN1KMT2ALMNAPOLBALDH1A1 | |
| SCHEMBL8263008 | 0.78 | MEN1 (0.47) | MCOLN3MEN1KMT2ATDP1LMNA | |
| SCHEMBL20111730 | 0.76 | SMYD3 (0.30) | — | |
| SCHEMBL24870380 | 0.75 | EPHX2 (0.36) | — | |
| SCHEMBL22174786 | 0.74 | KMT2A (0.40) | MCOLN3MEN1KMT2ATDP1LMNA | |
| SCHEMBL10280126 | 0.74 | KMT2A (0.40) | MCOLN3MEN1KMT2ATDP1LMNA | |
| SCHEMBL20111927 | 0.74 | MEN1 (0.44) | MCOLN3MEN1KMT2ATDP1LMNA | |
| SCHEMBL26793785 | 0.74 | KMT2A (0.40) | MCOLN3MEN1KMT2ATDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018078360-A1 | MODULATORS OF HEDGEHOG (HH) SIGNALLING PATHWAY | E-THERAPEUTICS PLC (GB) | 2018-05-03 | — | — | WO | disclosed |