Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EBP | Q15125 | 1/20 | 0.36 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8263008 | 0.86 | MEN1 (0.47) | MEN1KMT2ATDP1LMNAMCOLN3 | |
| SCHEMBL20111928 | 0.85 | MEN1 (0.33) | MEN1KMT2ATDP1LMNAMCOLN3 | |
| SCHEMBL15014594 | 0.82 | MEN1 (0.48) | MEN1KMT2ATDP1LMNAMCOLN3 | |
| SCHEMBL8263019 | 0.80 | EPHX2 (0.50) | MEN1KMT2ATDP1LMNAMCOLN3 | |
| SCHEMBL21732859 | 0.74 | MEN1 (0.39) | MEN1KMT2ATDP1LMNAMCOLN3 | |
| SCHEMBL20111636 | 0.74 | MCOLN3 (0.41) | MEN1KMT2ATDP1LMNAMCOLN3 | |
| SCHEMBL27329188 | 0.74 | ALDH1A1 (0.42) | MEN1KMT2ATDP1LMNAMCOLN3 | |
| SCHEMBL12634 | 0.73 | KDM4E (0.53) | MEN1KMT2ATDP1LMNAMCOLN3 | |
| SCHEMBL13621140 | 0.73 | MEN1 (0.48) | MEN1KMT2ATDP1LMNAMCOLN3 | |
| SCHEMBL3021365 | 0.73 | LMNA (0.50) | MEN1KMT2ATDP1LMNAMCOLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018078360-A1 | MODULATORS OF HEDGEHOG (HH) SIGNALLING PATHWAY | E-THERAPEUTICS PLC (GB) | 2018-05-03 | — | — | WO | disclosed |