Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.30 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20111927 | 0.85 | MEN1 (0.44) | MEN1KMT2ATDP1LMNAMCOLN3 | |
| SCHEMBL8263008 | 0.72 | MEN1 (0.47) | MEN1KMT2ATDP1LMNAEPHX2 | |
| SCHEMBL15431984 | 0.72 | TP53 (0.48) | MEN1KMT2ALMNAEPHX2KDM4E | |
| SCHEMBL20111642 | 0.69 | TP53 (0.53) | MEN1KMT2ATDP1LMNA | |
| SCHEMBL15014594 | 0.68 | MEN1 (0.48) | MEN1KMT2ATDP1LMNAEPHX2 | |
| SCHEMBL8263019 | 0.67 | EPHX2 (0.50) | MEN1KMT2ATDP1LMNAEPHX2 | |
| SCHEMBL26793785 | 0.64 | KMT2A (0.40) | MEN1KMT2ATDP1LMNAEPHX2 | |
| SCHEMBL22174786 | 0.64 | KMT2A (0.40) | MEN1KMT2ATDP1LMNAEPHX2 | |
| SCHEMBL16905072 | 0.64 | TP53 (0.41) | LMNAKDM4EPOLB | |
| SCHEMBL26176804 | 0.64 | TP53 (0.41) | LMNAKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018078360-A1 | MODULATORS OF HEDGEHOG (HH) SIGNALLING PATHWAY | E-THERAPEUTICS PLC (GB) | 2018-05-03 | — | — | WO | disclosed |