Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2516568 | 0.80 | — | — | |
| SCHEMBL20046964 | 0.80 | NEK2 (0.43) | PTPN11FPR2 | |
| SCHEMBL25060592 | 0.76 | FPR2 (0.36) | PTPN11FPR2 | |
| SCHEMBL18319559 | 0.76 | CRBN (0.35) | PTPN11FPR2 | |
| SCHEMBL20007912 | 0.76 | CYP2D6 (0.36) | PTPN11FPR2 | |
| SCHEMBL4228889 | 0.75 | PTPN11 (0.31) | PTPN11 | |
| SCHEMBL105607 | 0.74 | POLB (0.35) | — | |
| Hydrochloric Acid SCHEMBL19126647 | 0.72 | POLB (0.34) | — | |
| SCHEMBL340232 | 0.72 | NEK2 (0.38) | — | |
| SCHEMBL19094306 | 0.72 | HSD11B1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081091-A1 | PYRAZOLO[3,4-B]PYRAZINE DERIVATIVES AS SHP2 PHOSPHATASE INHIBITORS | RELAY THERAPEUTICS, INC. (US) | 2018-05-03 | — | — | WO | disclosed |