Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18646588 | 0.92 | FFAR1 (0.40) | MAPTKMT2AMEN1KDM4EMAPK1 | |
| SCHEMBL20112832 | 0.89 | MAPT (0.42) | MAPTKMT2AMEN1KDM4EMAPK1 | |
| SCHEMBL23052927 | 0.89 | MAPT (0.40) | MAPTKMT2AMEN1KDM4EMAPK1 | |
| SCHEMBL20312018 | 0.88 | GPR174 (0.41) | MAPTKMT2AMEN1KDM4EMAPK1 | |
| SCHEMBL19882314 | 0.88 | GPR174 (0.41) | MAPTKMT2AMEN1KDM4EMAPK1 | |
| SCHEMBL1098577 | 0.88 | ELANE (0.40) | KMT2ACYP2C19CTSA | |
| SCHEMBL26144157 | 0.88 | ELANE (0.40) | KMT2ACYP2C19CTSA | |
| SCHEMBL22023572 | 0.87 | GPR174 (0.40) | MAPTKMT2AMEN1KDM4EMAPK1 | |
| SCHEMBL22600499 | 0.86 | MEN1 (0.39) | MAPTKMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL18509891 | 0.86 | GPR174 (0.40) | MAPTKMT2AMEN1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10934487-B2 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2021-03-02 | — | — | US | disclosed |
| US-20180119010-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-05-03 | — | — | US | disclosed |