Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.42 |
| ▸ | MEN1 | O00255 | 10/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22023572 | 0.95 | GPR174 (0.40) | MAPTMAPK1KDM4EKMT2AMEN1 | |
| SCHEMBL18509891 | 0.94 | GPR174 (0.40) | MAPTMAPK1KDM4EKMT2AMEN1 | |
| SCHEMBL21655391 | 0.93 | KMT2A (0.40) | MAPTMAPK1KDM4EKMT2AMEN1 | |
| SCHEMBL20112746 | 0.91 | ELANE (0.40) | MAPTMAPK1KDM4EKMT2AMEN1 | |
| SCHEMBL20112831 | 0.89 | MAPT (0.42) | MAPTMAPK1KDM4EKMT2AMEN1 | |
| SCHEMBL19674629 | 0.89 | FFAR4 (0.44) | KMT2AHTTELANEPOLBCYP2C19 | |
| SCHEMBL25934094 | 0.88 | KMT2A (0.39) | MAPTMAPK1KDM4EKMT2AMEN1 | |
| SCHEMBL9607902 | 0.88 | ELANE (0.48) | MAPTKMT2AMEN1LMNAHPGD | |
| SCHEMBL18509898 | 0.87 | ELANE (0.43) | MAPTMAPK1KDM4EKMT2AMEN1 | |
| SCHEMBL9607894 | 0.87 | ELANE (0.47) | MAPTKMT2AMEN1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180119010-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-05-03 | — | — | US | disclosed |