SCHEMBL20112833

SCHEMBL20112833

C=C(C)COc1ccc2c(ccc3cc(OC(=O)C(=C)C)ccc32)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.45
ALDH1A1 P00352 3/20 0.45
MEN1 O00255 3/20 0.45
POLB P06746 3/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
PKM P14618 1/20 0.45
RECQL P46063 2/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ELANE P08246 1/20 0.41
PTPN7 P35236 1/20 0.41
GPR174 Q9BXC1 1/20 0.41
RAB9A P51151 3/20 0.39
ATM Q13315 1/20 0.39
HTT P42858 3/20 0.38
PPARG P37231 2/20 0.38
NCOA2 Q15596 2/20 0.38
NCOA1 Q15788 2/20 0.38
NCOA3 Q9Y6Q9 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19670076 0.94 ELANE (0.45) KMT2AALDH1A1MEN1POLBL3MBTL1
SCHEMBL23366170 0.90 ELANE (0.38) KMT2AALDH1A1MEN1POLBL3MBTL1
SCHEMBL802823 0.88 ELANE (0.50) KMT2AALDH1A1MEN1POLBL3MBTL1
SCHEMBL14957533 0.87 KMT2A (0.51) KMT2AALDH1A1MEN1POLBL3MBTL1
SCHEMBL21931160 0.84 ELANE (0.44) KMT2AMEN1POLBL3MBTL1RECQL
SCHEMBL20998247 0.84 ELANE (0.50) KMT2AALDH1A1MEN1POLBELANE
SCHEMBL18901011 0.83 ELANE (0.41) KMT2AALDH1A1MEN1POLBL3MBTL1
SCHEMBL18522453 0.82 KDM4E (0.46) KMT2AALDH1A1MEN1TSHRHSD17B10
SCHEMBL12321312 0.82 ELANE (0.45) KMT2AALDH1A1MEN1POLBL3MBTL1
SCHEMBL19882304 0.82 ACHE (0.43) KMT2AALDH1A1L3MBTL1RECQLMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11053354-B2 Liquid crystal display device SHARP KABUSHIKI KAISHA (JP) 2021-07-06 US disclosed
US-11008515-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2021-05-18 US disclosed
US-10851301-B2 Liquid crystal medium MERCK PATENT GMBH (DE) 2020-12-01 US disclosed
US-10669484-B2 Process of preparing a light modulation element MERCK PATENT GMBH (DE) 2020-06-02 US disclosed
EP-3119854-B1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2020-02-05 EP disclosed
EP-3502210-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2019-06-26 EP disclosed
US-20190161679-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2019-05-30 US disclosed
US-20180187081-A1 PROCESS OF PREPARING A LIGHT MODULATION ELEMENT MERCK PATENT GMBH (DE) 2018-07-05 US disclosed
US-9963637-B2 Liquid crystal medium MERCK PATENT GMBH (DE) 2018-05-08 US disclosed
US-20180119010-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2018-05-03 US disclosed