SCHEMBL19670076

SCHEMBL19670076

C=C(C)COc1ccc2cc(OC(=O)C(=C)C)ccc2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.45
PTPN7 P35236 1/20 0.45
GPR174 Q9BXC1 1/20 0.44
KMT2A Q03164 5/20 0.43
MEN1 O00255 4/20 0.43
POLB P06746 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
ALDH1A1 P00352 2/20 0.43
PKM P14618 1/20 0.43
RAB9A P51151 3/20 0.42
ATM Q13315 1/20 0.42
RECQL P46063 2/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
HSD17B10 Q99714 1/20 0.42
HTT P42858 4/20 0.41
PPARG P37231 2/20 0.41
NCOA2 Q15596 2/20 0.41
NCOA1 Q15788 2/20 0.41
NCOA3 Q9Y6Q9 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20112833 0.94 KMT2A (0.45) ELANEPTPN7GPR174KMT2AMEN1
SCHEMBL21931160 0.89 ELANE (0.44) ELANEPTPN7KMT2AMEN1POLB
SCHEMBL803231 0.87 ELANE (0.56) ELANEKMT2AMEN1POLBL3MBTL1
SCHEMBL21934994 0.85 ELANE (0.41) ELANEPTPN7KMT2AMEN1POLB
SCHEMBL22353025 0.84 MAPT (0.41) ELANEGPR174KMT2AMEN1POLB
SCHEMBL20112746 0.84 ELANE (0.40) ELANEGPR174KMT2AMEN1POLB
SCHEMBL23366170 0.84 ELANE (0.38) ELANEPTPN7GPR174KMT2AMEN1
SCHEMBL15302662 0.83 ELANE (0.53) ELANEKMT2AMEN1POLBL3MBTL1
SCHEMBL3566985 0.83 ELANE (0.53) ELANEKMT2AMEN1POLBL3MBTL1
SCHEMBL2121980 0.83 ELANE (0.53) ELANEKMT2AMEN1POLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11739266-B2 Polymerisable compounds and the use thereof in liquid-crystal displays MERCK PATENT GMBH (DE) 2023-08-29 US disclosed
EP-3720925-B1 WINDOW ELEMENT MERCK PATENT GMBH (DE) 2023-02-15 EP disclosed
US-20230002678-A1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2023-01-05 US disclosed
US-20180119010-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2018-05-03 US disclosed
US-9951274-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2018-04-24 US disclosed
US-9835890-B2 Liquid crystal display MERCK PATENG GMBH (DE) 2017-12-05 US disclosed