Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20113104 | 0.84 | GRM7 (0.74) | GRM7MEN1KMT2APRMT5WDR77 | |
| SCHEMBL20113106 | 0.84 | GRM7 (0.74) | GRM7MEN1KMT2APRMT5WDR77 | |
| SCHEMBL20112964 | 0.82 | GRM7 (0.49) | GRM7MEN1KMT2AALDH1A1 | |
| SCHEMBL20112963 | 0.82 | GRM7 (0.49) | GRM7SCN5ASCN9AKCNH2 | |
| SCHEMBL20113177 | 0.81 | GRM7 (0.52) | GRM7PRMT5WDR77SCN5ASCN9A | |
| SCHEMBL20113084 | 0.81 | GRM7 (0.66) | GRM7MEN1KMT2APRMT5WDR77 | |
| SCHEMBL20113077 | 0.79 | GRM7 (0.43) | GRM7MEN1KMT2AALDH1A1POLB | |
| SCHEMBL19960658 | 0.79 | GRM7 (0.43) | GRM7MEN1KMT2AALDH1A1POLB | |
| SCHEMBL19953523 | 0.79 | GRM7 (0.43) | GRM7MEN1KMT2AALDH1A1POLB | |
| SCHEMBL19960858 | 0.76 | GRM7 (0.40) | GRM7KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018079862-A1 | MGLUR7 MODULATORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-05-03 | — | — | WO | disclosed |