Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20113020 | 0.84 | GRM7 (0.68) | GRM7ALDH1A1KMT2AGAASMN1; SMN2 | |
| SCHEMBL20113178 | 0.82 | GRM7 (0.54) | GRM7ALDH1A1KMT2AMEN1 | |
| SCHEMBL20112963 | 0.82 | GRM7 (0.49) | GRM7 | |
| SCHEMBL20113104 | 0.74 | GRM7 (0.74) | GRM7ALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL20113019 | 0.74 | GRM7 (0.68) | GRM7ALDH1A1KMT2AXIAP | |
| SCHEMBL20113106 | 0.74 | GRM7 (0.74) | GRM7ALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL20113177 | 0.71 | GRM7 (0.52) | GRM7 | |
| SCHEMBL20113084 | 0.71 | GRM7 (0.66) | GRM7ALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL20113021 | 0.70 | GRM7 (0.78) | GRM7ALDH1A1KMT2AGAAMEN1 | |
| SCHEMBL20113080 | 0.70 | GRM7 (0.74) | GRM7ALDH1A1KMT2AGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018079862-A1 | MGLUR7 MODULATORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-05-03 | — | — | WO | disclosed |