Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 8/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 3/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16304973 | 0.84 | PTGER4 (0.50) | PTGER4MDM2GSK3BRORC | |
| SCHEMBL20113743 | 0.83 | PTGER4 (0.41) | PTGER4MDM2HDAC6MLYCDGSK3B | |
| SCHEMBL18843620 | 0.83 | PTGER4 (0.51) | PTGER4MDM2GSK3BRORC | |
| SCHEMBL16304978 | 0.83 | PTGER4 (0.51) | PTGER4MDM2GSK3BRORC | |
| SCHEMBL20113509 | 0.80 | PTGER4 (0.44) | PTGER4MDM2HDAC6MLYCDGSK3B | |
| SCHEMBL20113478 | 0.78 | PTGER4 (0.43) | PTGER4MDM2HDAC6MLYCDGSK3B | |
| SCHEMBL16304872 | 0.78 | AGTR2 (0.42) | PTGER4MDM2HDAC6MLYCDGSK3B | |
| SCHEMBL20113520 | 0.77 | PTGER4 (0.42) | PTGER4MDM2HDAC6MLYCDGSK3B | |
| SCHEMBL16304056 | 0.76 | PTGER4 (0.41) | PTGER4MDM2HDAC6MLYCDGSK3B | |
| SCHEMBL20114006 | 0.75 | MDM2 (0.44) | PTGER4MDM2GSK3BRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3009426-B1 | 4-ALKYNYL IMIDAZOLE DERIVATIVE AND MEDICINE COMPRISING SAME AS ACTIVE INGREDIENT | KAKEN PHARMA CO LTD (JP) | 2018-05-02 | — | — | EP | disclosed |