Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 3/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | SGK1 | O00141 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2011360 | 0.81 | NR3C1 (0.45) | NR3C1PIK3C3PGRSGK1RIPK1 | |
| SCHEMBL27780295 | 0.73 | NR3C1 (0.54) | NR3C1PIK3C3PGRSGK1ALDH1A1 | |
| SCHEMBL2004015 | 0.67 | NR3C1 (0.44) | NR3C1PIK3C3PGRSGK1LMNA | |
| SCHEMBL2008086 | 0.65 | NR3C1 (0.78) | NR3C1PIK3C3PGRSGK1 | |
| SCHEMBL2009788 | 0.64 | NR3C1 (0.58) | NR3C1PIK3C3PGRSGK1 | |
| SCHEMBL2006541 | 0.63 | NR3C1 (0.62) | NR3C1PIK3C3PGRSGK1 | |
| SCHEMBL27758653 | 0.62 | NR3C1 (0.49) | NR3C1PIK3C3PGRSGK1RORC | |
| SCHEMBL2008089 | 0.57 | NR3C1 (0.79) | NR3C1PIK3C3PGRSGK1 | |
| SCHEMBL391271 | 0.56 | POLB (0.40) | NR3C1PIK3C3PGRSGK1ALDH1A1 | |
| SCHEMBL16235124 | 0.56 | CCR2 (0.48) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960365-B2 | Compounds with medicinal effects due to interaction with the glucocorticoid receptor | N.V. ORGANON (NL) | 2011-06-14 | — | — | US | claimed |