Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 7/20 | 0.49 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.49 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78122 | 0.89 | PRKCA (0.59) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL76782 | 0.87 | ALDH1A1 (0.55) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL5308587 | 0.87 | ALDH1A1 (0.55) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| Glycerin SCHEMBL27553048 | 0.84 | PRKCA (0.46) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL15280953 | 0.83 | ALDH1A1 (0.49) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL17877418 | 0.81 | ALDH1A1 (0.50) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL2876718 | 0.80 | PRKCA (0.42) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL17470678 | 0.79 | ALDH1A1 (0.49) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL2402791 | 0.79 | ALDH1A1 (0.49) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL15198874 | 0.79 | ALDH1A1 (0.47) | PRKCAPRKCEPRKCQPRKCDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964378-B2 | Reacting a glyceride, an acetylated saccharide or other ester such a mono- or diester of a glycol with a source of peroxygen in the presence an enzyme of the CE-7 family of carbohydrate esterases, including cephalosporin acetyl hydrolases and acetyl xylan esterases | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-06-21 | — | — | US | claimed |