Sugi Predict

Sugi Predict / Compounds / SCHEMBL20114043

SCHEMBL20114043

SCHEMBL20114043

c1ccc(N2c3ccccc3Sc3cc(-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)ccc32)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 3/20 0.45
▸ KDM4E B2RXH2 1/20 0.45
▸ ATM Q13315 1/20 0.45
▸ HDAC6 Q9UBN7 1/20 0.36
▸ HDAC4 P56524 1/20 0.34
▸ BCHE P06276 4/20 0.33
▸ KMT2A Q03164 3/20 0.33
▸ ACHE P22303 2/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ ADRA2A P08913 1/20 0.33
▸ ADRA2B P18089 1/20 0.33
▸ ADRA2C P18825 1/20 0.33
▸ CHRM3 P20309 1/20 0.33
▸ SLC6A2 P23975 1/20 0.33
▸ HTR2C P28335 1/20 0.33
▸ SLC6A4 P31645 1/20 0.33
▸ DRD3 P35462 1/20 0.33
▸ HTR2B P41595 1/20 0.33
▸ NOX1 Q9Y5S8 1/20 0.33
▸ PTGER4 P35408 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10331707 1.00 L3MBTL1 (0.45) L3MBTL1KDM4EATMHDAC6HDAC4
SCHEMBL10331693 1.00 L3MBTL1 (0.45) L3MBTL1KDM4EATMHDAC6HDAC4
SCHEMBL10309966 0.98 L3MBTL1 (0.43) L3MBTL1KDM4EATMHDAC6HDAC4
SCHEMBL15470182 0.96 L3MBTL1 (0.42) L3MBTL1KDM4EATMHDAC6HDAC4
SCHEMBL20114282 0.96 L3MBTL1 (0.42) L3MBTL1KDM4EATMHDAC6HDAC4
SCHEMBL20114048 0.96 L3MBTL1 (0.42) L3MBTL1KDM4EATMHDAC6HDAC4
SCHEMBL20114042 0.96 L3MBTL1 (0.42) L3MBTL1KDM4EATMHDAC6HDAC4
SCHEMBL10331570 0.96 HDAC6 (0.38) L3MBTL1KDM4EATMHDAC6BCHE
SCHEMBL10331573 0.96 L3MBTL1 (0.49) L3MBTL1KDM4EATMHDAC6HDAC4
SCHEMBL20114386 0.95 L3MBTL1 (0.40) L3MBTL1KDM4EATMHDAC6HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220144856-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-05-12 — — US disclosed
US-20210328150-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, ORGANIC ELECTROLUMINESCENT MATERIAL COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-21 — — US disclosed
US-20210280796-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, ORGANIC ELECTROLUMINESCENT MATERIAL COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-09-09 — — US disclosed
WO-2018080067-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING SAME 주식회사 두산 2018-05-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210280796-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, ORGANIC ELECTROLUMINESCENT MATERIAL COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE OR10J3, ELAVL1, VDAC2 L3MBTL1 82/4885KDM4E 1212/4885ATM 2041/4885
US-20220144856-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, L1CAM, EPCAM L3MBTL1 110/4885KDM4E 2347/4885ATM 1746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.