SCHEMBL20114065

SCHEMBL20114065

c1ccc(N2c3ccccc3Oc3cc(-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)ccc32)cc1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.45
KDM4E B2RXH2 1/20 0.45
ATM Q13315 1/20 0.45
EDNRA P25101 7/20 0.37
EDNRB P24530 3/20 0.37
HDAC4 P56524 1/20 0.34
PTGER4 P35408 1/20 0.33
P2RX4 Q99571 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSPO P30536 1/20 0.32
KMT2A Q03164 1/20 0.32
IL1R1 P14778 1/20 0.32
CDK8 P49336 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
KDR P35968 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10331688 1.00 L3MBTL1 (0.45) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL10331703 1.00 L3MBTL1 (0.45) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL10309959 0.98 L3MBTL1 (0.43) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL15470144 0.96 L3MBTL1 (0.42) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL20114090 0.96 L3MBTL1 (0.42) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL20114040 0.96 L3MBTL1 (0.42) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL20114134 0.96 KDM4E (0.42) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL10331571 0.96 KDM4E (0.38) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL10331572 0.96 L3MBTL1 (0.49) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL20114117 0.95 L3MBTL1 (0.40) L3MBTL1KDM4EATMEDNRAEDNRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220144856-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-05-12 US disclosed
US-20210328150-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, ORGANIC ELECTROLUMINESCENT MATERIAL COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-21 US disclosed
US-20210280796-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, ORGANIC ELECTROLUMINESCENT MATERIAL COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-09-09 US disclosed
WO-2018080067-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING SAME 주식회사 두산 2018-05-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210280796-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, ORGANIC ELECTROLUMINESCENT MATERIAL COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE OR10J3, ELAVL1, VDAC2 L3MBTL1 82/4885KDM4E 1212/4885ATM 2041/4885
US-20220144856-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, L1CAM, EPCAM L3MBTL1 110/4885KDM4E 2347/4885ATM 1746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.