SCHEMBL2011410

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Hydrochloric Acid SCHEMBL2009760	0.98	SIGMAR1 (0.56)	SIGMAR1SMN1; SMN2POLBCHRM5CHRM3
	SCHEMBL3997780	0.84	SIGMAR1 (0.52)	SIGMAR1SMN1; SMN2POLBCHRM5CHRM3
	SCHEMBL23869788	0.78	SMN1; SMN2 (0.41)	SIGMAR1SMN1; SMN2POLBCHRM5CHRM3
	SCHEMBL665674	0.77	SIGMAR1 (0.61)	SIGMAR1POLBCHRM5CHRM3ALDH1A1
	SCHEMBL7748189	0.76	SIGMAR1 (0.54)	SIGMAR1SMN1; SMN2POLBCHRM5CHRM3
	SCHEMBL24029891	0.75	SIGMAR1 (0.52)	SIGMAR1POLBCHRM5CHRM3ALDH1A1
	SCHEMBL5863	0.75	SIGMAR1 (0.56)	SIGMAR1CHRM5CHRM3ALDH1A1MEN1
	Hydrochloric Acid SCHEMBL17271878	0.73	ALDH1A1 (0.54)	SIGMAR1SMN1; SMN2CHRM5CHRM3ALDH1A1
	Piperazine SCHEMBL28845954	0.73	SIGMAR1 (0.54)	SIGMAR1CHRM5CHRM3ALDH1A1MEN1
	Hydrochloric Acid SCHEMBL963162	0.73	ALDH1A1 (0.54)	SIGMAR1SMN1; SMN2CHRM5CHRM3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.