Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB3 | Q16875 | 14/20 | 0.76 |
| ▸ | PFKFB4 | Q16877 | 12/20 | 0.72 |
| ▸ | CMA1 | P23946 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL788594 | 0.86 | PFKFB3 (1.00) | PFKFB3PFKFB4CMA1NPSR1L3MBTL1 | |
| SCHEMBL787994 | 0.84 | PFKFB3 (0.77) | PFKFB3PFKFB4CMA1 | |
| SCHEMBL788512 | 0.84 | PFKFB3 (0.77) | PFKFB3PFKFB4CMA1 | |
| SCHEMBL787998 | 0.84 | PFKFB3 (0.80) | PFKFB3PFKFB4CMA1 | |
| SCHEMBL788108 | 0.84 | PFKFB4 (1.00) | PFKFB3PFKFB4CMA1NPSR1L3MBTL1 | |
| SCHEMBL788304 | 0.83 | PFKFB3 (0.76) | PFKFB3PFKFB4CMA1 | |
| SCHEMBL787908 | 0.82 | PFKFB3 (0.74) | PFKFB3PFKFB4CMA1 | |
| SCHEMBL788169 | 0.82 | PFKFB3 (1.00) | PFKFB3PFKFB4 | |
| Propane SCHEMBL28642185 | 0.81 | PFKFB4 (0.94) | PFKFB3PFKFB4CMA1NPSR1L3MBTL1 | |
| SCHEMBL788755 | 0.79 | PFKFB3 (0.68) | PFKFB3PFKFB4CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616450-B1 | SULFONAMIDE COMPOUNDS | KANCERA AB (SE) | 2018-05-02 | — | — | EP | disclosed |