Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18455367 | 0.68 | NISCH (0.49) | NISCHIDO1METAP2RAB9AL3MBTL1 | |
| SCHEMBL31471473 | 0.67 | ACHE (0.69) | NISCHIDO1METAP2RAB9AALDH1A1 | |
| SCHEMBL301247 | 0.67 | ACHE (0.69) | NISCHIDO1METAP2RAB9AALDH1A1 | |
| SCHEMBL29373699 | 0.67 | ACHE (0.69) | NISCHIDO1METAP2RAB9AALDH1A1 | |
| SCHEMBL11984411 | 0.66 | MAPK14 (0.51) | RAB9AL3MBTL1ALDH1A1HPGDNPC1 | |
| SCHEMBL19577801 | 0.65 | ACHE (0.65) | NISCHIDO1METAP2RAB9AALDH1A1 | |
| SCHEMBL18797759 | 0.65 | ACHE (0.65) | NISCHIDO1METAP2RAB9AALDH1A1 | |
| SCHEMBL9855192 | 0.64 | NISCH (0.53) | NISCHIDO1METAP2RAB9AL3MBTL1 | |
| SCHEMBL12264968 | 0.63 | RAB9A (0.54) | IDO1METAP2RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL11337633 | 0.63 | NISCH (1.00) | NISCHACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616450-B1 | SULFONAMIDE COMPOUNDS | KANCERA AB (SE) | 2018-05-02 | — | — | EP | disclosed |