Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB4 | Q16877 | 13/20 | 0.78 |
| ▸ | PFKFB3 | Q16875 | 12/20 | 0.78 |
| ▸ | TCF4 | P15884 | 2/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL788343 | 0.88 | PFKFB4 (1.00) | PFKFB4PFKFB3TCF4CTNNB1POLB | |
| SCHEMBL787754 | 0.82 | PFKFB4 (1.00) | PFKFB4PFKFB3TCF4CTNNB1POLB | |
| SCHEMBL788176 | 0.80 | PFKFB4 (1.00) | PFKFB4PFKFB3POLBWDR5 | |
| SCHEMBL787889 | 0.76 | PFKFB3 (0.72) | PFKFB4PFKFB3TCF4CTNNB1CMA1 | |
| SCHEMBL788203 | 0.73 | PFKFB3 (0.77) | PFKFB4PFKFB3TCF4CTNNB1CMA1 | |
| SCHEMBL787986 | 0.73 | PFKFB3 (1.00) | PFKFB4PFKFB3TCF4CTNNB1CMA1 | |
| SCHEMBL787869 | 0.73 | PFKFB3 (1.00) | PFKFB4PFKFB3CMA1 | |
| SCHEMBL788058 | 0.72 | PFKFB3 (1.00) | PFKFB4PFKFB3CMA1 | |
| SCHEMBL787888 | 0.71 | PFKFB3 (1.00) | PFKFB4PFKFB3CMA1 | |
| SCHEMBL787993 | 0.71 | PFKFB4 (1.00) | PFKFB4PFKFB3POLBWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616450-B1 | SULFONAMIDE COMPOUNDS | KANCERA AB (SE) | 2018-05-02 | — | — | EP | disclosed |