SCHEMBL20114628

SCHEMBL20114628

c1cc(-c2ccc3c(c2)Sc2ccccc2N3c2cccc3c2oc2ccccc23)cc(-c2ccc3c4ccccc4n(-c4cccc5c4oc4ccccc45)c3c2)c1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.32
PRKDC P78527 1/20 0.31
PLA2G2A P14555 1/20 0.31
PLA2G4A P47712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20114872 0.92 KDM4E (0.31) ALOX5PLA2G2APLA2G4A
SCHEMBL20114832 0.92 ALOX5 (0.33) ALOX5PRKDC
SCHEMBL20114409 0.92 PLA2G2A (0.30) PLA2G2APLA2G4A
SCHEMBL20114289 0.92
SCHEMBL20114629 0.92 KDM4E (0.30) PLA2G2APLA2G4A
SCHEMBL20114204 0.91
SCHEMBL20114631 0.89 TSHR (0.30)
SCHEMBL20114633 0.89 TSHR (0.30)
SCHEMBL20114411 0.88
SCHEMBL20114630 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018080067-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING SAME 주식회사 두산 2018-05-03 WO disclosed