SCHEMBL20115500

SCHEMBL20115500

CCN(CC)C(=O)C(F)(F)C(C)C

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 4/20 0.36
LMNA P02545 1/20 0.34
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP3 P08254 1/20 0.33
MMP8 P22894 1/20 0.33
HTR1A P08908 1/20 0.32
DPP4 P27487 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10973690 0.82 MLYCD (0.36) MLYCDLMNACHRM2CHRM4CHRM5
SCHEMBL249531 0.75 MLYCD (0.45) MLYCDLMNACHRM2CHRM4CHRM5
SCHEMBL17967109 0.74 DPP4 (0.36) LMNAMMP1MMP2MMP3MMP8
SCHEMBL6116244 0.74 MLYCD (0.37) MLYCDLMNAMMP1MMP2MMP3
SCHEMBL24050929 0.73 CHRM2 (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL21235948 0.73 MLYCD (0.39) MLYCDLMNAMMP1MMP2MMP3
SCHEMBL11326641 0.73 LMNA (0.34) LMNAMMP1MMP2MMP3MMP8
SCHEMBL15058548 0.71 MLYCD (0.42) MLYCDLMNAMMP1MMP2MMP3
SCHEMBL28418104 0.71 MLYCD (0.38) MLYCDLMNAMMP1MMP2MMP3
SCHEMBL20115678 0.71 MLYCD (0.41) MLYCDLMNAMMP1MMP2MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2170975-B1 COMPOSITIONS AND METHODS FOR PRODUCING CELLULAR LABELS FOR NUCLEAR MAGNETIC RESONANCE TECHNIQUES UNIV CARNEGIE MELLON (US) 2018-05-02 EP disclosed