Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20115878 | 0.91 | ALKBH5 (0.47) | ALKBH5FTOKDM4EMAPTGPR3 | |
| SCHEMBL26226125 | 0.89 | KDM4E (0.40) | ALKBH5FTOKDM4EMAPTGPR3 | |
| SCHEMBL16791290 | 0.86 | GPR3 (0.61) | ALKBH5FTOKDM4EMAPTGPR3 | |
| SCHEMBL10450123 | 0.86 | GPR3 (0.61) | ALKBH5FTOKDM4EMAPTGPR3 | |
| SCHEMBL11940264 | 0.86 | GPR3 (0.61) | ALKBH5FTOKDM4EMAPTGPR3 | |
| SCHEMBL22906563 | 0.86 | GPR3 (0.46) | ALKBH5FTOKDM4EMAPTGPR3 | |
| SCHEMBL23373459 | 0.85 | KDM4E (0.55) | KDM4EMAPTGPR3L3MBTL1HTT | |
| SCHEMBL25943019 | 0.85 | KDM4E (0.40) | ALKBH5FTOKDM4EMAPTGPR3 | |
| SCHEMBL26310628 | 0.85 | KDM4E (0.37) | ALKBH5FTOKDM4EMAPTL3MBTL1 | |
| SCHEMBL4402782 | 0.85 | KDM4E (0.55) | ALKBH5FTOKDM4EMAPTGPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3061759-B1 | NITRILE SUBSTITUTED DIBENZOFURANS | IDEMITSU KOSAN CO (JP) | 2019-12-25 | — | — | EP | disclosed |
| EP-3119770-B1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | IDEMITSU KOSAN CO (JP) | 2018-05-02 | — | — | EP | disclosed |