Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | RORA | P35398 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | RORB | Q92753 | 1/20 | 0.33 |
| ▸ | PON1 | P27169 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | NR2E3 | Q9Y5X4 | 2/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15801370 | 0.94 | MAPT (0.39) | ALDH1A1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL18707389 | 0.93 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4EHTTHPGD | |
| SCHEMBL16920067 | 0.92 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4EHTTHPGD | |
| SCHEMBL15785780 | 0.92 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4EHTTHPGD | |
| SCHEMBL15959668 | 0.90 | KDM4E (0.40) | ALDH1A1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL18707249 | 0.89 | ALDH1A1 (0.45) | ALDH1A1MAPTKDM4EHTTHPGD | |
| SCHEMBL17993385 | 0.89 | KDM4E (0.41) | ALDH1A1MAPTKDM4EHTTHPGD | |
| SCHEMBL17850761 | 0.89 | KDM4E (0.41) | ALDH1A1MAPTKDM4EHTTHPGD | |
| SCHEMBL19961382 | 0.88 | KIF11 (0.42) | MAPTMEN1KMT2APPARGRXFP1 | |
| SCHEMBL19961390 | 0.87 | MAOB (0.37) | ALDH1A1MAPTKDM4EHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119770-B1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | IDEMITSU KOSAN CO (JP) | 2018-05-02 | — | — | EP | disclosed |