Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28051627 | 0.83 | AR (0.70) | ARMEN1KMT2ACLK1DYRK1A | |
| SCHEMBL30355317 | 0.80 | DYRK1A (0.54) | ARMEN1NPC1POLBKMT2A | |
| SCHEMBL9714208 | 0.80 | DYRK1A (0.54) | ARMEN1NPC1POLBKMT2A | |
| SCHEMBL26442543 | 0.79 | AR (0.47) | ARBCHENPC1CLK1DYRK1A | |
| SCHEMBL13267003 | 0.78 | KIF11 (0.67) | BCHEMEN1NPC1POLBKMT2A | |
| SCHEMBL29726988 | 0.78 | KIF11 (0.67) | BCHEMEN1NPC1POLBKMT2A | |
| SCHEMBL20115838 | 0.78 | MEN1 (0.47) | MEN1NPC1POLBKMT2ACLK1 | |
| SCHEMBL20115833 | 0.77 | DYRK1A (0.47) | ARCLK1DYRK1A | |
| SCHEMBL29732438 | 0.77 | DYRK1A (0.47) | ARCLK1DYRK1A | |
| SCHEMBL28641040 | 0.76 | KDM4E (0.49) | ARBCHEMEN1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119770-B1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | IDEMITSU KOSAN CO (JP) | 2018-05-02 | — | — | EP | disclosed |