Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16140964 | 1.00 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL12855787 | 0.85 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL184319 | 0.85 | — | — | |
| Ammonia Solution, Strong SCHEMBL8076657 | 0.82 | — | — | |
| SCHEMBL18493173 | 0.78 | — | — | |
| SCHEMBL10486140 | 0.77 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL2754726 | 0.77 | — | — | |
| SCHEMBL10486147 | 0.77 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL75081 | 0.77 | — | — | |
| SCHEMBL5150085 | 0.74 | NPC1 (0.44) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081294-A1 | PYRAZOLE AMIDE COMPOUNDS AS IRAK INHIBITORS | RIGEL PHARMACEUTICALS, INC. (US) | 2018-05-03 | — | — | WO | disclosed |