Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 3/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116694 | 0.89 | GRM5 (0.36) | SMN1; SMN2LMNATSHRGRM5KIT | |
| SCHEMBL20116100 | 0.88 | LDHA (0.41) | SMN1; SMN2LMNATSHRGRM5KIT | |
| SCHEMBL20116818 | 0.87 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNATSHRGRM5KIT | |
| SCHEMBL20116363 | 0.87 | SMO (0.37) | HDAC6SMN1; SMN2TSHRKITHTT | |
| SCHEMBL20116362 | 0.87 | MAPT (0.37) | SMN1; SMN2LMNATSHRGRM5KIT | |
| SCHEMBL20117070 | 0.85 | GRM5 (0.40) | GRM5 | |
| SCHEMBL20116762 | 0.85 | KIT (0.38) | SMN1; SMN2LMNATSHRGRM5KIT | |
| SCHEMBL20116348 | 0.85 | GRM5 (0.41) | GRM5 | |
| SCHEMBL20116358 | 0.83 | KIT (0.36) | GRM5KITMAPT | |
| SCHEMBL20116695 | 0.83 | GRM5 (0.35) | GRM5KITPTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |