Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.57 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116214 | 0.84 | PRSS1 (0.54) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL12287386 | 0.82 | DGAT1 (0.50) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL1300394 | 0.82 | HSD17B2 (0.65) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL20116491 | 0.81 | PDE4B (0.56) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL9219136 | 0.77 | DGAT1 (0.53) | ALDH1A1LMNAL3MBTL1USP2PRSS1 | |
| SCHEMBL21823575 | 0.76 | PRSS1 (0.54) | PDE4APDE4BPDE4CPDE4DHSD17B10 | |
| Hydrochloric Acid SCHEMBL2461112 | 0.75 | HSD17B2 (0.45) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL27014428 | 0.75 | PRKCI (0.54) | ALDH1A1HTTGAAPRSS1DGAT1 | |
| SCHEMBL13108706 | 0.75 | DGAT1 (0.62) | ALDH1A1LMNAHTTCYP3A4SMN1; SMN2 | |
| SCHEMBL11177279 | 0.75 | TSHR (0.63) | ALDH1A1CYP3A4NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |