Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.56 |
| ▸ | PDE4A | P27815 | 3/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116214 | 0.86 | PRSS1 (0.54) | PDE4BPDE4APDE4CPDE4DHSD17B2 | |
| SCHEMBL18346603 | 0.82 | CA12 (0.65) | HSD17B2RECQLDGAT1CA12CA1 | |
| SCHEMBL20116490 | 0.81 | PDE4A (0.57) | PDE4BPDE4APDE4CPDE4DTUBB1 | |
| SCHEMBL460455 | 0.81 | HSD17B2 (0.77) | PDE4BPDE4APDE4CPDE4DHSD17B2 | |
| SCHEMBL14042191 | 0.81 | PDE4B (0.54) | PDE4BPDE4APDE4CPDE4DRECQL | |
| SCHEMBL760141 | 0.79 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4DHSD17B2 | |
| SCHEMBL9219136 | 0.78 | DGAT1 (0.53) | HSD17B2DGAT1TSHRALOX12MEN1 | |
| SCHEMBL21823575 | 0.78 | PRSS1 (0.54) | PDE4BPDE4APDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL2461112 | 0.77 | HSD17B2 (0.45) | PDE4BPDE4APDE4CPDE4DHSD17B2 | |
| SCHEMBL13108706 | 0.77 | DGAT1 (0.62) | HSD17B2RECQLDGAT1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |