Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2011662 | 1.00 | HTT (0.42) | HTTAKR1C3AKR1C2TBXAS1GAA | |
| SCHEMBL16585493 | 0.82 | HTT (0.43) | HTTAKR1C3AKR1C2TBXAS1GAA | |
| SCHEMBL16585492 | 0.82 | HTT (0.43) | HTTAKR1C3AKR1C2TBXAS1GAA | |
| SCHEMBL1114486 | 0.81 | ALDH1A1 (0.42) | ALDH1A1CYP3A4CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL23630588 | 0.81 | ALDH1A1 (0.42) | ALDH1A1CYP3A4CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL16876656 | 0.81 | HTT (0.42) | HTTAKR1C3AKR1C2TBXAS1GAA | |
| SCHEMBL30895153 | 0.81 | HTT (0.42) | HTTAKR1C3AKR1C2TBXAS1GAA | |
| SCHEMBL7769274 | 0.79 | HTT (0.44) | HTTAKR1C3AKR1C2TBXAS1GAA | |
| SCHEMBL7754416 | 0.78 | F7 (0.45) | HTTAKR1C3AKR1C2TBXAS1GAA | |
| SCHEMBL4960058 | 0.74 | NOTUM (0.44) | HTTAKR1C3AKR1C2TBXAS1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960349-B2 | N-terminally modified GLP-1 receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-06-14 | — | — | US | disclosed |