Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5692597 | 0.81 | TRPM8 (0.42) | LMNAL3MBTL1 | |
| SCHEMBL16585492 | 0.75 | HTT (0.43) | NOTUMGAAHTTKCNA5KDM4E | |
| SCHEMBL16585493 | 0.75 | HTT (0.43) | NOTUMGAAHTTKCNA5KDM4E | |
| SCHEMBL16876656 | 0.74 | HTT (0.42) | NOTUMGAAHTTKCNA5KDM4E | |
| SCHEMBL2011662 | 0.74 | HTT (0.42) | NOTUMGAAHTTKCNA5KDM4E | |
| SCHEMBL2011663 | 0.74 | HTT (0.42) | NOTUMGAAHTTKCNA5KDM4E | |
| SCHEMBL30895153 | 0.74 | HTT (0.42) | NOTUMGAAHTTKCNA5KDM4E | |
| SCHEMBL7769274 | 0.73 | HTT (0.44) | GAAHTTKCNA5KDM4ELMNA | |
| SCHEMBL7754416 | 0.71 | F7 (0.45) | GAAHTTKCNA5KDM4EAKR1C3 | |
| SCHEMBL13338411 | 0.71 | CFTR (0.47) | HTTKCNA5KDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883652-A2 | N-TERMINALLY MODIFIED GLP-1 RECEPTOR MODULATORS | Bristol-Myers Squibb Company (US) | 2008-02-06 | — | — | EP | disclosed |
| WO-2006127948-A2 | N-TERMINALLY MODIFIED GLP-1 RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-11-30 | — | — | WO | disclosed |