Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26998422 | 0.87 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPTGAAMAPK1THRB | |
| SCHEMBL20116655 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTGAAMAPK1THRB | |
| SCHEMBL20116262 | 0.83 | MAPT (0.59) | SMN1; SMN2MAPTGAAMAPK1THRB | |
| SCHEMBL20117011 | 0.82 | MAPT (0.61) | SMN1; SMN2MAPTGAAMAPK1THRB | |
| SCHEMBL26998415 | 0.81 | MAPT (0.53) | SMN1; SMN2MAPTGAAMAPK1THRB | |
| SCHEMBL20116601 | 0.79 | MAPT (0.57) | SMN1; SMN2MAPTMAPK1THRBNPC1 | |
| SCHEMBL20116597 | 0.77 | MAPT (0.67) | SMN1; SMN2MAPTGAAMAPK1THRB | |
| SCHEMBL30506255 | 0.77 | MAPT (0.67) | SMN1; SMN2MAPTGAAMAPK1THRB | |
| SCHEMBL20116544 | 0.76 | SMN1; SMN2 (0.73) | SMN1; SMN2MAPTMAPK1NPC1HSD17B10 | |
| SCHEMBL20116543 | 0.76 | SMN1; SMN2 (0.73) | SMN1; SMN2MAPTMAPK1NPC1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777121-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-110099898-B | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2023-07-25 | — | — | CN | disclosed |
| US-20200262828-A1 | COMPOUNDS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2020-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200262828-A1 | COMPOUNDS AND USES THEREOF | NLN, ACHE, CLN6 | SMN1; SMN2 13/4885MAPT 22/4885GAA 67/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.