Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 3/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.30 |
| ▸ | FASN | P49327 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22357935 | 0.84 | PIK3CD (0.36) | KITPIK3CDBRD4CREBBPPTGER3 | |
| SCHEMBL20116152 | 0.84 | KIT (0.40) | KITSMOPTGER3HDAC4FASN | |
| SCHEMBL20676639 | 0.82 | MAPT (0.37) | PIK3CDBRD4CREBBPPTGER3CDK8 | |
| SCHEMBL22357929 | 0.82 | KIT (0.36) | KITSMOPTGER3HDAC4FASN | |
| SCHEMBL20116156 | 0.82 | KIT (0.36) | KITSMOPTGER3HDAC4FASN | |
| SCHEMBL22357933 | 0.82 | HDAC4 (0.43) | HDAC4 | |
| SCHEMBL20116148 | 0.82 | KIT (0.36) | KITSMOPTGER3HDAC4FASN | |
| SCHEMBL20116155 | 0.81 | GPR119 (0.36) | KITSMOPIK3CDPTGER3 | |
| SCHEMBL20117183 | 0.81 | MAPT (0.40) | PIK3CDPTGER3 | |
| SCHEMBL20116749 | 0.79 | NR1H4 (0.45) | SMOPTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |