Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116142 | 0.88 | POLB (0.60) | KMT2AMEN1SMN1; SMN2RAB9ATSHR | |
| SCHEMBL21609968 | 0.87 | KMT2A (0.52) | KMT2AMEN1SMN1; SMN2RAB9ATSHR | |
| SCHEMBL21609969 | 0.87 | KMT2A (0.51) | KMT2AMEN1SMN1; SMN2RAB9ATSHR | |
| SCHEMBL20116652 | 0.87 | KMT2A (0.51) | KMT2AMEN1SMN1; SMN2RAB9ATSHR | |
| SCHEMBL20676549 | 0.85 | KMT2A (0.52) | KMT2AMEN1SMN1; SMN2RAB9ATSHR | |
| SCHEMBL20116446 | 0.85 | KMT2A (0.57) | KMT2AMEN1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL30506338 | 0.85 | KMT2A (0.57) | KMT2AMEN1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL20116498 | 0.83 | RAB9A (0.52) | KMT2AMEN1SMN1; SMN2RAB9ATSHR | |
| SCHEMBL20116234 | 0.76 | ALDH1A1 (0.63) | KMT2ASMN1; SMN2TSHRKDM4EALDH1A1 | |
| SCHEMBL20116457 | 0.76 | POLB (0.78) | KMT2ASMN1; SMN2TSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019209948-A9 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-01-02 | — | — | WO | disclosed |
| WO-2019018795-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2019-01-24 | — | — | WO | disclosed |
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |