Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD5 | P21918 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25616870 | 0.86 | MAOA (0.40) | MAOAMAOBDRD2DRD1DRD4 | |
| SCHEMBL17624284 | 0.85 | AADAT (0.36) | JAK2AADAT | |
| SCHEMBL24329407 | 0.83 | AADAT (0.33) | JAK2AADAT | |
| SCHEMBL26997354 | 0.79 | AADAT (0.31) | AADAT | |
| SCHEMBL15980400 | 0.78 | MAOA (0.45) | MAOAMAOBDRD2DRD1DRD4 | |
| SCHEMBL19256651 | 0.74 | HDAC8 (0.40) | AADAT | |
| SCHEMBL12250991 | 0.74 | HDAC8 (0.43) | AADAT | |
| SCHEMBL19040098 | 0.73 | AADAT (0.36) | JAK2AADAT | |
| SCHEMBL18034940 | 0.72 | MAOA (0.40) | MAOAMAOBDRD2DRD1DRD4 | |
| SCHEMBL24817957 | 0.72 | OGA (0.36) | DRD2JAK2AADAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |