Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2016473 | 0.86 | GRM5 (0.61) | GRM5 | |
| SCHEMBL2012693 | 0.81 | GRM5 (0.57) | GRM5 | |
| SCHEMBL2011099 | 0.78 | GRM5 (0.77) | GRM5 | |
| SCHEMBL157209 | 0.71 | GRM5 (0.57) | GRM5 | |
| SCHEMBL155658 | 0.70 | GRM5 (0.53) | GRM5 | |
| SCHEMBL2011208 | 0.69 | GRM5 (0.53) | GRM5 | |
| SCHEMBL158425 | 0.69 | GRM5 (0.53) | GRM5 | |
| SCHEMBL156464 | 0.69 | GRM5 (0.52) | GRM5 | |
| SCHEMBL2009451 | 0.68 | GRM5 (0.61) | GRM5 | |
| SCHEMBL15246690 | 0.67 | GRM5 (0.48) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513117-A1 | BICYCLIC THIAZOLES AS ALLOSTERIC MODULATORS OF MGLUR5 RECEPTORS | Janssen Pharmaceutica, N.V. (BE) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011073339-A1 | BICYCLIC THIAZOLES AS ALLOSTERIC MODULATORS OF MGLUR5 RECEPTORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-06-23 | — | — | WO | disclosed |