Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | IDH1 | O75874 | 8/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2235912 | 0.79 | DDB1 (0.38) | BRD4P2RX7SCD5 | |
| SCHEMBL16181380 | 0.79 | MDM2 (0.48) | — | |
| SCHEMBL2235902 | 0.79 | DDB1 (0.38) | BRD4P2RX7SCD5 | |
| SCHEMBL16181385 | 0.79 | CYP19A1 (0.45) | — | |
| SCHEMBL5286742 | 0.78 | IDH1 (0.43) | IDH1 | |
| SCHEMBL5281444 | 0.78 | IDH1 (0.43) | IDH1 | |
| SCHEMBL2615701 | 0.78 | IDH1 (0.43) | IDH1 | |
| SCHEMBL2308887 | 0.76 | KDM1A (0.47) | — | |
| SCHEMBL2236980 | 0.75 | LMNA (0.48) | — | |
| SCHEMBL2236969 | 0.75 | LMNA (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349990-B1 | ARYL-PHENYL-SULFONAMIDE-PHENYLENE COMPOUNDS AND THEIR USE | PIMCO 2664 LTD (GB) | 2018-05-02 | — | — | EP | disclosed |