Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.44 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2241472 | 0.90 | MCL1 (0.45) | PTGES2AVPR2GPR27L3MBTL1ALDH1A1 | |
| SCHEMBL2234241 | 0.90 | MCL1 (0.45) | PTGES2AVPR2GPR27L3MBTL1ALDH1A1 | |
| SCHEMBL2236007 | 0.90 | MCL1 (0.45) | PTGES2AVPR2GPR27L3MBTL1ALDH1A1 | |
| SCHEMBL10093362 | 0.89 | L3MBTL1 (0.46) | PTGES2AVPR2GPR27L3MBTL1ALDH1A1 | |
| SCHEMBL2241383 | 0.88 | SCN9A (0.48) | PTGES2AVPR2GPR27L3MBTL1ALDH1A1 | |
| SCHEMBL10093393 | 0.87 | HDAC4 (0.44) | PTGES2AVPR2GPR27L3MBTL1ALDH1A1 | |
| SCHEMBL20117530 | 0.87 | L3MBTL1 (0.46) | PTGES2AVPR2GPR27L3MBTL1ALDH1A1 | |
| SCHEMBL10093057 | 0.84 | ALDH1A1 (0.46) | PTGES2AVPR2GPR27L3MBTL1ALDH1A1 | |
| SCHEMBL2237975 | 0.84 | ADRB3 (0.46) | AVPR2GPR27L3MBTL1ALDH1A1ESR1 | |
| SCHEMBL2240766 | 0.83 | SCN9A (0.43) | PTGES2AVPR2GPR27L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349990-B1 | ARYL-PHENYL-SULFONAMIDE-PHENYLENE COMPOUNDS AND THEIR USE | PIMCO 2664 LTD (GB) | 2018-05-02 | — | — | EP | disclosed |