Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.44 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.44 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19932362 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAERAP1L3MBTL1DNMT1 | |
| SCHEMBL19932327 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAERAP1L3MBTL1DNMT1 | |
| SCHEMBL20117643 | 0.94 | LMNA (0.57) | ALDH1A1LMNAERAP1L3MBTL1DNMT1 | |
| SCHEMBL19932398 | 0.91 | LMNA (0.53) | ALDH1A1LMNAERAP1L3MBTL1DNMT1 | |
| SCHEMBL19921882 | 0.91 | LMNA (0.53) | ALDH1A1LMNAERAP1L3MBTL1DNMT1 | |
| SCHEMBL20117914 | 0.90 | LMNA (0.52) | ALDH1A1LMNAERAP1L3MBTL1DNMT1 | |
| SCHEMBL19932328 | 0.90 | LMNA (0.66) | ALDH1A1LMNAERAP1L3MBTL1DNMT1 | |
| SCHEMBL19932342 | 0.90 | LMNA (0.52) | ALDH1A1LMNAERAP1L3MBTL1DNMT1 | |
| SCHEMBL21323075 | 0.90 | LMNA (0.52) | ALDH1A1LMNAERAP1L3MBTL1DNMT1 | |
| SCHEMBL19921881 | 0.90 | LMNA (0.66) | ALDH1A1LMNAERAP1L3MBTL1DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018079855-A1 | PHARMACEUTICAL COMPOSITION FOR INDUCING PROGRAMMED CELL DEATH IN CANCER CELLS | 国立大学法人京都大学 | 2018-05-03 | — | — | WO | disclosed |